Welchol (Colesevelam) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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Generic alternative for Welchol


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Colesevelam is prescribed in conjunction with proper diet and exercise to reduce cholesterol levels in individuals with high cholesterol in their bloodstream. By lowering cholesterol levels, the likelihood of heart disease, strokes, and heart attacks is reduced. In individuals with type 2 diabetes, colesevelam is used to reduce high blood sugar levels, thereby preventing kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

This medication belongs to the class of drugs known as bile acid-binding resins, which operate by removing bile acid from the body, leading to the liver producing more bile acid by using cholesterol, which lowers cholesterol levels in the bloodstream. The precise mechanism by which colesevelam reduces blood sugar levels remains unclear.

Uses and Dosage

Colesevelam is available in three forms: tablets, chewable bars, and powder to be mixed with a liquid and taken orally. Generally, tablets are taken once or twice daily with meals and a drink, while chewable bars and powder are taken once a day with a meal. Colesevelam should be taken exactly as directed, without taking more or less of it or taking it more frequently than prescribed.

In the case of the powder form, the entire contents of one packet should be emptied into a glass and mixed with 8 ounces of water, fruit juice, or a diet soft drink. The mixture should be stirred thoroughly, and the entire contents of the glass should be consumed, even if the contents appear cloudy and do not dissolve fully. Do not take the powder in its dry form.

If taking chewable bars, it is worth noting that each bar contains 80 calories.

While colesevelam can manage medical conditions, it does not cure them. Continue taking the medication even when feeling well and not to cease taking it without consulting a physician.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • gas
  • constipation
  • nausea
  • vomiting
  • diarrhea
  • heartburn
  • stomach or back pain
  • headache
  • weakness
  • muscle pain

Inform your healthcare provider immediately if you experience any serious side effects:

  • severe abdominal pain with or without nausea and vomiting


Prior to initiating treatment with colesevelam, inform your healthcare provider or pharmacist of any known allergies you may have, as well as any other allergies. This product may contain inactive ingredients that can provoke allergic reactions or other issues.

When using this medication, disclose your medical history to your healthcare provider or pharmacist, particularly if you have experienced pancreatitis due to high triglyceride levels, high triglyceride levels, difficulty swallowing, gastrointestinal disorders, recent significant intestinal surgery, or hemorrhoids.

Given that this medication can impede the absorption of certain vitamins (such as vitamins A, D, E, K) over extended periods, your healthcare provider may direct you to take a multivitamin supplement. It is suggested that you take the multivitamin at least 4 hours prior to your colesevelam dose.

The powder form of this medication may contain aspartame. If you have phenylketonuria (PKU) or any other condition that necessitates the restriction of aspartame, please consult your healthcare provider or pharmacist to ensure the safe use of this medication.

If you are pregnant, inform your healthcare provider before taking this medication.

This medication is not likely to enter breast milk or harm a nursing infant. Consult your healthcare provider prior to breastfeeding.

Form and Strength

Welchol is available in the following forms and strengths:

  • colesevelam tablet:

    • 625mg


How long does it take for Welchol to make me feel better?

With Welchol, you may start seeing some results in as little as 2 weeks.

Can you take Welchol long term?

If Welchol works well to treat your condition, your doctor will likely recommend that you take it long term. The drug is a safe and effective treatment option for lowering cholesterol and blood sugar levels.


  1. https://welchol.com/how-welchol-works#:~:text=With%20Welchol%2C%20you%20may%20start,as%20little%20as%202%20weeks
  2. https://www.medicalnewstoday.com/articles/drugs-welchol#fa-qs
  3. https://www.mayoclinic.org/drugs-supplements/colesevelam-oral-route/side-effects/drg-20063133?p=1
  4. https://www.webmd.com/drugs/2/drug-19893/welchol-oral/details
  5. https://medlineplus.gov/druginfo/meds/a699050.html
  6. https://www.drugs.com/mtm/welchol.html

Additional information

Generic name:

Colesevelam, Colesevelam Hydrochloride





Quantities Available:

180, 360, 540

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Welchol (Colesevelam). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Welchol (Colesevelam).