Ziana (Clindamycin Phosphate/Tretinoin) Customer Reviews


Rx Prescription Required    RxFormulation : Topical Gel

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What is Biacna topical gel used for? 

This gel is a topical combo medicine that contains clindamycin phosphate and tretinoin. This drug belongs to lincosamide antibiotics and retinoids to treat acne vulgaris. This medication is only for people over the age of 12. 

This medication is available in 1.2/0.025 % concentration.

How does Biacna work? 

Bacteria are usually present in the face, specifically in the follicle. When the sebaceous gland is overactive, it produces excessive oil, clogging the area. When your pores become clogged, germs become trapped within and produce fatty acids that can irritate your skin. 

This obstruction can cause your follicles to become too stretched. When overstretched, it can burst follicles and become a source of infection. As a result, redness and inflammation manifest as pimples or acne. 

Biacna topical gel is composed of two acne-fighting ingredients that work in tandem. Clindamycin phosphate is an antibiotic that aids in the prevention of bacterial growth on the skin. However, Tretinoin promotes the shedding of dead skin or the outer layer of the skin and reduces oil buildup. It also helps by unclogging your pores, eliminating extra oils, and reducing the formation of blackheads which is beneficial for clearing up zits.

Best way to use Biacna gel 

Check all prescription directions and information carefully. Use the drug exactly as directed. Consult your doctor or pharmacist if you have any questions about using this topical gel. 

In applying this gel before and after use, thoroughly wash your hands. Also, when washing your face, use a gentle soap or cleanser, paying attention to the affected area. Rinse thoroughly with lukewarm water and wipe dry with a clean cloth. 

Apply a pea-sized or small amount of this topical treatment to your face. Spread it evenly and massage it gently once a day in the evening or as directed by your doctor. 

This topical gel should be used only externally and should not be taken orally or applied to the eyes, nostrils, mouth, or open wounds. Excessive dosing will not improve your skin condition any faster and could increase your risk of suffering undesirable side effects. 

If the treatment did not work as well as you had hoped or did not improve your condition, you should see and call your doctor.

Biacna Gel Side Effects 

The following are the common side effects of this drug that may resolve with time without medical intervention: 

  • Headache 
  • Sunburn 
  • Upper respiratory tract infections 
  • Mild skin irritation, dryness, or peeling 
  • Skin discoloration

If any of these side effects worsen over time or if you experience any of the following adverse reactions, contact your doctor immediately: 

  • Blistering 
  • Crusted skin 
  • Severe irritation or burning sensation in the affected site 
  • Bloody diarrhea
  • Unbearable stomach pain
  • Inflammation of the colon 

Bear in mind that this is not all the list of the potential health concerns linked with this medication.


Tell your doctor if you have eczema, a history of antibiotic-induced colitis, Crohn’s disease, or small intestine inflammation. This medication may worsen your underlying medical condition. 

If you are allergic to any of the following: clindamycin, lincomycin, tretinoin, or other ingredients, do not use this drug. When using this medication, you should seek medical advice as soon as you notice any of the following signs and symptoms: rashes, hives, swelling of the face and lips, throat tightness, or difficulty breathing. 

Do not use this topical mediation if you have scratches, lacerations, or burns. Doing so can increase the absorption of the medication in the skin, which can cause you to experience more unwanted effects of the medicine. 

Use caution if you are using this medication because it may make you more sensitive to sunlight. When you’re going outside, it is advisable to avoid direct sunlight and wear protective clothing and sunscreen (SPF 30 or above). 

Medications containing erythromycin products, whether used topically or taken orally, should not be combined with Biacna since drug interactions may arise. Before using any medication, consult with your doctor first. 

Keep this item out of children’s reach and store it accordingly.

How much does Biacna gel cost? 

The cost of Biacna is relatively justifiable. You may purchase this medication from us for a fast and easy transaction.

Frequently Asked Questions 

Will applying Biacna gel cause my skin to purge? 

The outcomes differ from person to person. However, you may experience worsening of your acne during the first few weeks of using Biacna gel. The full therapeutic effect can be seen several weeks later. Do not stop this medication without the consent of your physician.

Is it safe to use other acne treatments together with Biacna gel? 

Do not combine Biacna gel with other acne medications. It is discouraged since it may exacerbate and increase the skin irritation effect of both drugs.

Can I get Biacna gel without a prescription? 

When purchasing Biacna gel, you must receive a prescription from your doctor.

Is it safe to use Biacna gel when pregnant? 

Biacna gel should not be used during pregnancy as it may affect your unborn child. Remember that the advantages of this medicine must outweigh the disadvantages. It is strongly advised to utilize birth control techniques while using this drug to avoid pregnancy. 

Additional information

Generic name:

Clindamycin Phosphate/Tretinoin


Topical Gel



Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Ziana (Clindamycin Phosphate/Tretinoin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Ziana (Clindamycin Phosphate/Tretinoin).