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Formulation : 
Description
Indications
Simvastatin is commonly used in combination with a well-balanced diet to assist in reducing levels of “bad” cholesterol and fats, such as LDL and triglycerides, while also increasing levels of “good” cholesterol, or HDL, within the bloodstream. This medication is classified as a member of the statin family of drugs, which operate by decreasing the amount of cholesterol produced by the liver. By lowering levels of “bad” cholesterol and triglycerides while increasing levels of “good” cholesterol, the risk of heart disease is reduced, and the likelihood of stroke or heart attack is lessened.
Uses and Dosage
To ensure optimal results, take this medication exactly as prescribed by your physician, typically once per day in the evening.
If taking the tablet form of this medication, it may be taken with or without food.
For the liquid form of this medication, it should be taken on an empty stomach. Prior to each dose, shake the bottle for at least 20 seconds. Use a special measuring device/spoon to accurately measure the dose, and refrain from using a household spoon as the dose may not be precise.
The dosage of this medication is dependent on various factors, including your medical condition, response to treatment, age, and any other medications you may be taking.
Typically, the maximum daily dose for this medication is 40 milligrams. If directed by your physician to take more than 40 milligrams, continue with the same dose but discuss the potential risks and benefits with your doctor.
Do not increase your dosage or take this medication more frequently than prescribed, as it will not expedite the recovery process and may increase the likelihood of adverse side effects.
While taking this medication, avoid consuming grapefruit or grapefruit juice unless instructed otherwise by your doctor, as grapefruit can raise the levels of this medication in your bloodstream.
To achieve the greatest benefit from this medication, take it regularly at the same time each day, even if you are feeling well. Continue following your doctor’s recommendations regarding diet and exercise, and it may take up to 4 weeks to realize the full effects of this drug.
Side Effects
Some side effects may occur that usually do not need medical attention:
- constipation
- stomach pain
- nausea
- headache
- memory loss or forgetfulness
- confusion
- itchy or red skin
Inform your healthcare provider immediately if you experience any serious side effects:
- muscle pain, tenderness, or weakness with or without fever or lack of energy
- dark red urine
- decreased urination
- lack of energy, tiredness, or weakness
- loss of appetite
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- dark colored urine
- fever or chills
- flushing
- blisters
- rash
- hives
- itching
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty breathing or swallowing
- hoarseness
- joint pain
- sensitivity to light
Caution
Before taking simvastatin, inform your doctor or pharmacist if you have any allergies, including an allergy to this medication or any of its inactive ingredients, which may lead to an allergic reaction or other complications.
Prior to using this medication, discuss your medical history with your doctor or pharmacist, particularly if you have liver or kidney disease or consume alcohol regularly.
Limit your alcohol consumption while taking this medication. Combining daily alcohol use with simvastatin may raise your risk for liver problems.
The elderly population may be more prone to experiencing side effects from this medication, particularly muscle problems.
During pregnancy, use of this medication should be limited to situations where there is a clear necessity. Simvastatin may pose a risk to the unborn fetus. Consult with your doctor to weigh the potential risks and benefits.
It is not known whether this medication passes into breast milk. Due to the possible risks to the infant, it is not recommended to breastfeed while using this medication.
Form and Strength
Zocor is available in the following forms and strengths:
-
Zocor film-coated tablet:
- 10mg
- 20mg
- 40mg
-
simvastatin tablet:
- 5mg
- 10mg
- 20mg
- 40mg
- 80mg
FAQ
Is Zocor better than Lipitor?
Both Lipitor and Zocor are good for lowering LDL, but Zocor is better at increasing HDL and tends to have fewer gastrointestinal side effects, according to one study.
Should I take Zocor at night or morning?
Statins are best taken at night.
Resources
- https://www.medicinenet.com/atorvastatin_lipitor_vs_simvastatin_zocor/drug-vs.htm
- https://www.healthline.com/health/high-cholesterol/why-should-you-take-statins-at-night#:~:text=These%20statins%20are%20best%20taken,it%27s%20taken%20in%20the%20morning
- https://www.medbroadcast.com/drug/getdrug/zocor
- https://www.webmd.com/drugs/2/drug-6040/zocor-oral/details
- https://medlineplus.gov/druginfo/meds/a692030.html
- https://www.drugs.com/zocor.html
