Zostrix HP (Capsaicin - non Rx) Customer Reviews

Zostrix HP

Rx Prescription Required    RxFormulation : Cream

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Topical capsaicin is employed to alleviate minor pain in muscles and joints stemming from conditions such as arthritis, backaches, muscle strains, bruises, cramps, and sprains. Capsaicin, a substance found in chili peppers, is the active component in this topical application. It operates by influencing nerve cells in the skin that are linked to pain perception, leading to decreased activity of these nerve cells and a diminished sensation of pain.

Uses and Dosage

Capsaicin is available in various forms, including ointment, cream, gel, oil, and a topical solution, with different strengths for application to the skin. Typically, it is used as needed, as indicated on the product label or as directed by your doctor.

Use topical capsaicin precisely as directed, avoiding using more or less of it or using it more frequently than instructed by the package guidelines.

To apply topical capsaicin, take a small amount of ointment, cream, oil, or topical solution and spread it thinly over the affected area of the skin. Gently rub it in, and avoid applying it to folds of the skin.

Do not use topical capsaicin on skin that is broken, damaged, cut, infected, or covered by a rash. Additionally, refrain from wrapping or bandaging the treated area.

This medication is intended for use only on the skin. Avoid getting topical capsaicin into your eyes, nose, or mouth, and do not swallow it.

After application, wash your hands with soap and water to remove any residual medicine. If you’ve applied topical capsaicin to your hands, wait for 30 minutes before washing them. Refrain from touching your eyes, nose, or mouth until your hands are washed.

While using topical capsaicin, shield the treated area from direct heat, such as heating pads, electric blankets, hair dryers, and heat lamps. It’s advisable not to apply topical capsaicin immediately before or after showering, taking a bath, swimming, or engaging in vigorous exercise.

If your pain worsens, improves and then worsens again, or lasts longer than 7 days, stop using topical capsaicin and contact your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • burning sensation at the place where capsaicin was applied
  • redness, itching, or irritation at the place where capsaicin was applied
  • cough
  • sneezing
  • throat irritation

Inform your healthcare provider immediately if you experience any serious side effects:

  • pain, swelling, or blistering at the place where capsaicin was applied
  • eye irritation or pain


  • Before using capsaicin, inform your doctor or pharmacist if you are allergic to it, zucapsaicin, hot peppers (from the Capsicum family), lidocaine, or other local anesthetics that may be present in your specific brand, or if you have any other allergies. Inactive ingredients in the product may cause allergic reactions or other issues.
  • If you have any health problems, consult your doctor or pharmacist before using this medication.
  • For individuals planning to undergo an MRI test, inform testing personnel if you are using the patch. Some patches may contain metals that could lead to serious burns during an MRI. Seek guidance from your doctor on whether you need to remove your patch before the test, apply a new patch afterward, and the proper way to do so.
  • During pregnancy, use this medication only when clearly necessary. Discuss the risks and benefits with your doctor.
  • It is unknown whether this medication passes into breast milk. Consult your doctor before breastfeeding.

Form and Strength

Zostrix HP is available in the following forms and strengths:

  • Zostrix HP cream:
    • 0.08 %


How long does it take for Zostrix HP to work?

You should begin to get pain relief within the first two weeks of treatment, but the maximum effect may take a month to build up as Zostrix cream works gradually.

What is the difference between Zostrix and Zostrix HP?

There are 2 strengths of capsaicin cream, which have different uses. 0.025% (called Zostrix) is used to relieve pain in osteoarthritis. 0.075% (called Zostrix HP) is used to relieve nerve pain caused by shingles or diabetes.


  1. https://www.medsafe.govt.nz/consumers/cmi/z/Zostrix.pdf
  2. https://healthify.nz/medicines-a-z/c/capsaicin/#:~:text=There%20are%202%20strengths%20of,diabetes%20(diabetic%20peripheral%20neuropathy)
  3. https://www.mayoclinic.org/drugs-supplements/capsaicin-topical-route/description/drg-20062561
  4. https://www.webmd.com/drugs/2/drug-6042/zostrix-hp-topical/details
  5. https://medlineplus.gov/druginfo/meds/a620055.html
  6. https://www.drugs.com/cdi/zostrix-hp.html

Additional information

Generic name:

Capsaicin – non Rx





Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Zostrix HP (Capsaicin - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Zostrix HP (Capsaicin - non Rx).