Norethindrone is indicated for the treatment of women with abnormal uterine bleeding, amenorrhea (absence of menstrual periods for several months), and endometriosis, a condition characterized by the presence of uterine tissue outside the uterus that results in painful or irregular periods.
Norethindrone belongs to the class of progestins, which are female hormones similar to progesterone naturally produced by the body. It acts by inhibiting the normal growth of the uterine lining during the menstrual cycle and inducing hormonal changes in the uterus to restore regular menstrual periods.
Uses and Dosage
Norethindrone is administered orally in the form of tablets. The dosage schedule of norethindrone is contingent on the specific medical condition being treated and the response to treatment.
In cases of endometriosis, it is taken once daily for a period of 6 to 9 months or until breakthrough bleeding becomes disruptive.
To induce menstruation in women who have stopped menstruating, it is typically taken once daily for 5 to 10 days during the second half of the planned menstrual cycle.
Take norethindrone at the same time each day as scheduled. Carefully follow the instructions on your prescription label, and seek clarification from your healthcare provider or pharmacist if any aspect of the directions is unclear. Do not exceed the prescribed dosage or frequency of norethindrone.
In instances of endometriosis, it is likely that your physician will initiate treatment with a low dose and gradually increase the dose, no more than once every two weeks.
While norethindrone may help alleviate symptoms, it does not provide a cure. Even if you feel better, continue taking norethindrone as directed by your doctor. Do not discontinue use without first consulting with your doctor.
Some side effects may occur that usually do not need medical attention:
- irregular vaginal bleeding or spotting
- changes in menstrual flow
- enlarged or tender breasts
- weight changes
- difficulty falling asleep or staying asleep
- brown patches on the face
- hair loss
- growth of hair on face
Inform your healthcare provider immediately if you experience any serious side effects:
- loss of vision
- blurred vision
- double vision
- bulging eyes
- migraine headache
- pain, warmth, or heaviness in the back of the lower leg
- shortness of breath
- coughing up blood
- sudden sharp or crushing chest pain
- heaviness in chest
- slow or difficult speech
- dizziness or faintness
- weakness or numbness of an arm or leg
- swelling of the arms, hands, feet, ankles, or lower legs
- yellowing of the skin or eyes
- mood swings
- missed periods
- sudden, severe pain in the abdomen (area between the chest and waist)
- difficulty breathing or swallowing
Prior to taking norethindrone, inform your doctor or pharmacist about any allergies you may have or any other allergies to medication. This product may contain inactive ingredients that could result in allergic reactions or other complications.
Prior to taking this medication, notify your doctor or pharmacist about your medical history, particularly vaginal bleeding of unknown origin, brain bleeding, a previous miscarriage with some remaining uterine tissue, family history of breast lumps/cancer or blood clots, obesity, heart disease, high blood pressure, cancer, blood clots, lupus, seizures, migraine headaches, asthma, liver disease, kidney problems, high levels of cholesterol/fats in the blood, depression, diabetes, or strokes.
This medication can cause dizziness. The consumption of alcohol or marijuana can exacerbate this effect. Avoid operating heavy machinery, driving or performing tasks that require full alertness until you can safely perform them.
Smoking is contraindicated while taking this medication. The combined use of norethindrone and smoking increases the risk of strokes, blood clots, high blood pressure, and heart attacks.
This medication may cause dark, blotchy areas on the skin and face (melasma). This effect may worsen with exposure to sunlight. Limit your exposure to sunlight and avoid tanning booths and sunlamps. When outside, wear protective clothing and use sunscreen.
This medication should not be used during pregnancy. If you suspect you may be pregnant or become pregnant, promptly inform your doctor.
This drug is excreted in breast milk. Consult your doctor prior to breastfeeding.
Form and Strength
Aygestin is available in the following forms and strengths:
How quickly does Aygestin stop my period?
The bleeding usually stops within 1 week.
Do you still ovulate on Aygestin?
Taken daily, Aygestin helps prevent ovulation and changes the cervical and uterine linings to prevent sperm movement and fertilized egg attachment.