This medicine is a first-line treatment of breast cancer in postmenopausal women.Store at room temperature in a cool dry place, protect from heat and light. Keep all medicines out of the reach of children and pets.How much medicine you take and how often you take it depend on many factors, including the condition being treated and the age and weight of the patient. If you have any questions about the amount and/or frequency of the medicine you are taking, talk with your health care provider. Do not stop taking this medicine without checking with your health care provider. Patients with previous medical conditions should talk with their health care provider before taking this medicine. Do not take more medicine than prescribed unless advised to do so by your health care provider. Do not take any other over-the-counter or prescription medications without talking with your health care provider. If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. If more than one dose is missed, contact your health care provider or pharmacist.Do not take this medicine if you are allergic to any component present in this medicine if you are pregnant..Before using this medicine, tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any prescription or nonprescription medicine if you are taking blood thinners if you have stomach problems if you have peptic ulcers if you have any other medical condition like liver or kidney function impairment or heart problemThis medicine may increase your blood cholesterol levels. Certain drugs like Tamoxafen and estrogen containing drugs reduce the effectiveness of this medicine.Most severe: Allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)Most common: Abdominal pain, accidental injury, anxiety, arthritis, back pain, bone pain, breast pain, cataracts, chest pain, constipation, cough, depression, diarrhea, dizziness, dry mouth, flu-like symptoms, fractures, headache, heart disease, high bloOther: Blood clots, bronchitis, confusion, drowsiness, feeling of illness, fever, hair thinning, heart attack, increased appetite, itching, muscle pain, nasal or sinus inflammation, neck pain, nervousness, severe blisters in the mouth or other mucous membranes, sluggishness, stroke, temporary tumor growth, tense muscles, vaginal bleeding, vaginal dryness, weight loss.