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Formulation : 
Description
Indications
This medication is prescribed to manage high blood pressure, aiming to lower it and thereby reduce the risk of strokes, heart attacks, and kidney problems. It comprises two active ingredients: cilazapril and hydrochlorothiazide. Cilazapril, classified as an ACE inhibitor, functions by easing the tension in blood vessels, facilitating smoother blood circulation throughout the body. Hydrochlorothiazide, also known as a thiazide diuretic, boosts urine production, eliminating excess water and salt from the body. This process contributes to the relaxation of blood vessels, further enhancing blood flow.
Uses and Dosage
Take this medication orally with or without food as directed by your doctor, typically once or twice daily. If you ingest this medication too close to bedtime, it may prompt you to wake up to urinate. You should take this medication at least 4 hours before bedtime.
If you are also using cholestyramine or colestipol, ensure there’s a gap of at least 4 hours before or after taking cilazapril/hydrochlorothiazide.
The prescribed dosage is contingent upon your medical condition and response to treatment.
Maintain regular use of this medication to maximize its benefits. To aid in remembering, take it at the same time(s) each day.
Continue taking this medication even if you feel well, as many individuals with high blood pressure do not experience symptoms of illness. It may take several weeks before the full therapeutic effects of this drug become apparent.
Inform your doctor if your condition worsens, such as an increase in routine blood pressure readings.
Side Effects
Some side effects may occur that usually do not need medical attention:
- abdominal pain
- cold-like symptoms (e.g., runny nose, nasal congestion, sneezing)
- constipation
- cough (dry, persistent)
- decreased appetite
- diarrhea
- dizziness
- drowsiness
- flushing
- headache
- increased frequency of urination
- increased sweating
- joint pain
- nausea
- rash, itching
- swollen mouth
- taste changes
- trouble sleeping
Inform your healthcare provider immediately if you experience any serious side effects:
- unusual tiredness
- vomiting
- weakness
- dizziness
- lightheadedness
- fainting
- increased heart rate
- lupus-like symptoms
- skin rash (with or without itching, fever, or joint pain)
- chest pain
- difficulty swallowing or breathing
Caution
- Before taking this product, inform your doctor or pharmacist if you have allergies to cilazapril, hydrochlorothiazide, other ACE inhibitors (such as captopril, lisinopril), other thiazides (such as chlorothiazide), or any other substances. Inactive ingredients in this product could potentially trigger allergic reactions or other complications.
- Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of allergic reactions involving swelling of the face/lips/tongue/throat (angioedema), kidney problems, blood transfusions, liver disease, gout, untreated electrolyte imbalances, dehydration, lupus, or skin cancer.
- This medication may cause dizziness. Alcohol or marijuana can intensify this effect. Avoid driving, operating machinery, or engaging in activities requiring alertness until you can do so safely.
- To minimize the risk of dizziness and lightheadedness, rise slowly when transitioning from a sitting or lying position.
- Stay hydrated while taking this medication to help prevent dizziness. Excessive sweating, diarrhea, or vomiting may lead to lightheadedness. Refrain from vigorous exercise. Inform your doctor of prolonged diarrhea or vomiting.
- This medication may heighten your sensitivity to sunlight and increase the risk of skin cancer, especially with prolonged use. Limit sun exposure, avoid tanning beds and sunlamps, use sunscreen, and wear protective clothing when outdoors.
- Promptly inform your doctor if you experience sunburn, skin blisters/redness, or notice new or changed moles/skin lesions.
- This product may affect your potassium levels. Consult your doctor or pharmacist before using potassium supplements or salt substitutes containing potassium.
- If you have diabetes, this product may elevate your blood sugar levels. Monitor your blood sugar regularly as directed and share the results with your doctor. Notify your doctor immediately if you experience symptoms of high blood sugar, such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise regimen, or diet.
- Older adults may be more susceptible to the side effects of this medication, particularly dizziness and changes in urine output (kidney problems).
- Inform your doctor if you are pregnant or planning to become pregnant. You should not become pregnant while using cilazapril/hydrochlorothiazide, as it may harm an unborn baby. If pregnancy occurs, promptly discuss the risks and benefits of this medication with your doctor.
- This medication passes into breast milk. Consult your doctor before breastfeeding.
Form and Strength
Inhibace Plus is available in the following forms and strengths:
- Inhibace Plus (form):
- 5 mg / 12.5 mg
- hydrochlorothiazide and cilazapril (form):
- 5 mg / 12.5 mg
FAQ
What is the best time of day to take Inhibace Plus?
Inhibace Plus can be taken at any time of day, as long as it is taken at consistent times each day.
Can you drink alcohol while taking Inhibace Plus?
Alcohol should be avoided while taking this medication. The interaction of alcohol with Inhibace Plus can make you dizzy.
