Mirabegron is indicated for the treatment of specific bladder disorders, including overactive bladder and neurogenic detrusor overactivity.
Overactive bladder is a condition where there is an issue with the storage of urine in the bladder, while neurogenic detrusor overactivity is caused by disruptions in the brain, spinal cord, or nerves. These conditions can result in frequent urination, strong and uncontrollable urges to urinate, or involuntary loss of urine (incontinence).
Mirabegron functions by relaxing the detrusor muscle in the bladder, enabling the bladder to store more urine and alleviating the symptoms associated with overactive bladder and neurogenic detrusor overactivity.
Uses and Dosage
Mirabegron is available in the form of an extended-release tablet and extended-release suspension for oral administration. The recommended dose for adults is to take the tablet once daily with or without food. Children are advised to take the tablet with food, once daily.
The extended-release suspension is to be taken with food, once daily. The extended-release tablets should be swallowed whole with water, without splitting, chewing, or crushing. Maintain a consistent dosing schedule and follow the instructions provided on the prescription label closely.
To accurately measure the dose of the extended-release suspension, use the provided oral dosing device. The bottle should be shaken vigorously for one minute, then allowed to stand for one to two minutes until the foam on top of the suspension has dissipated. If the granules have not mixed well, repeat the shaking process. Using the oral dosing device, measure the suspension, disregarding any bubbles in the measurement. The prepared dose should be used within one hour and should not be saved for later use.
Mirabegron is not a cure for overactive bladder or neurogenic detrusor overactivity, but rather a control for symptoms. The full benefit of Mirabegron may take eight weeks or longer to be felt. It is important to continue taking Mirabegron even if you feel well and to not discontinue the medication without consulting your doctor.
Some side effects may occur that usually do not need medical attention:
- back pain
- body aches or pain
- difficulty having a bowel movement
- difficulty with breathing
- difficulty with moving
- dry mouth
- ear congestion
- general feeling of discomfort or illness
- loss of voice
- muscle ache or stiffness
- stomach pain
- stuffy or runny nose
Inform your healthcare provider immediately if you experience any serious side effects:
- bladder pain
- bloody or cloudy urine
- blurred vision
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
- pounding in the ears
- slow, fast, or irregular heartbeat
Prior to taking Mirabegron, inform your physician or pharmacist if you have an allergy to the medication or any other allergies. This medication may contain inactive ingredients that can cause allergic reactions or other complications.
Advise your doctor or pharmacist of your medical history, particularly if you have a history of other bladder issues (such as obstruction), high blood pressure, kidney problems, or liver problems before using this medication.
This medication may cause dizziness. The combination of alcohol or marijuana can increase dizziness. Avoid operating heavy machinery, driving or performing tasks that require alertness until you are sure you can do so safely.
While pregnant, only use this medication if it is deemed necessary by your doctor. The risks and benefits should be discussed prior to use.
Form and Strength
Myrbetriq is available in the following forms and strengths:
Does Myrbetriq relax the bladder?
Myrbetriq works by relaxing smooth muscles in your bladder. This helps the bladder store more urine, helping relieve symptoms of OAB.
Is Myrbetriq hard on the liver?
Mirabegron has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.