Alka-Seltzer (Aspirin/Sodium Bicarbonate/Anhydrous Citric Acid - non Rx) Customer Reviews


Rx Prescription Required    RxFormulation :

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Alka-Seltzer is an antacid that is used for the treatment of symptoms associated with excessive stomach acid, including heartburn and indigestion. This medication may be prescribed by a healthcare professional to regulate the acidity levels of blood or urine in specific conditions.

Note that Alka-Seltzer may have additional uses beyond those described, and it is advisable to consult with a healthcare professional or pharmacist for further information.

Uses and Dosage

Strictly adhere to the directions provided on the prescription label when administering Alka-Seltzer. If there are any unclear instructions, seek clarification from the healthcare provider or a pharmacist.

When used as an antacid, Alka-Seltzer should be taken 1 to 2 hours after meals with a full glass of water. If prescribed for other purposes, it may be taken with or without food. Avoid consuming Alka-Seltzer on a completely full stomach.

Powdered sodium bicarbonate should be dissolved in at least 4 ounces (120 milliliters) of water, and the dose should be measured carefully using a measuring spoon.

Note that sodium bicarbonate should not be used for a duration exceeding 2 weeks, unless instructed otherwise by a doctor. If symptoms do not improve, a healthcare provider should be consulted.

Side Effects

Some common side effects associated with Alka-Seltzer include:

  • increased thirst
  • stomach cramps
  • gas

If you experience any of the following symptoms, discontinue the use of Alka-Seltzer and seek medical attention:

  • severe headache
  • nausea
  • vomit that resembles coffee grounds
  • loss of appetite
  • irritability
  • weakness
  • frequent urge to urinate
  • slow breathing
  • swelling of feet or lower legs
  • bloody, black, or tarry stools
  • blood in your urine


Prior to administering Alka-Seltzer, inform your healthcare provider or pharmacist of any allergies you may have. This medication may contain inactive ingredients, including but not limited to milk or dairy products, which may elicit an allergic response or other adverse effects.

If you have a history of hypercalcemia, gastrointestinal blockage, or kidney disease such as kidney stones, consult your healthcare provider or pharmacist before using this medication.

Note that some formulations of calcium carbonate may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame or phenylalanine, consult your healthcare provider or pharmacist for safe usage recommendations.

If you are pregnant, inform your healthcare provider before using this medication. Alka-Seltzer may be present in breast milk, consult your healthcare provider prior to breastfeeding.

Form and Strength

Alka-Seltzer is available in the following forms and strengths:

  • Alka-Seltzer tablet:

    • dissolvable in water


Should I take Alka-Seltzer with cold water?

Room temperature water works best, since cold water slows the dissolution and warm water can make the product foam excessively.

How long does it take Alka-Seltzer to dissolve?

After the Alka-Seltzer tablet was added to water it should have quickly dissolved, taking some 20 to 30 seconds to do so, depending on the exact temperature.



Additional information

Generic name:

Aspirin/Sodium Bicarbonate/Anhydrous Citric Acid – non Rx





Quantities Available:

24, 36

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Alka-Seltzer (Aspirin/Sodium Bicarbonate/Anhydrous Citric Acid - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Alka-Seltzer (Aspirin/Sodium Bicarbonate/Anhydrous Citric Acid - non Rx).