Canasa (Mesalamine) Customer Reviews


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Mesalamine is prescribed for the treatment of ulcerative proctitis, which is a form of inflammatory bowel disease. While it does not provide a cure for ulcerative proctitis, it is effective in reducing the frequency of bowel movements, minimizing the presence of mucus and blood in stools, and alleviating rectal bleeding resulting from colon or rectum inflammation and irritation.

Mesalamine belongs to the class of aminosalicylate anti-inflammatory drugs and is thought to exert its therapeutic effects by inhibiting the synthesis of specific endogenous substances that contribute to pain and swelling.

Uses and Dosage

Adhere to the following guidelines for the rectal administration of this medication. If you have the 1000-milligram strength, insert it rectally once daily at bedtime. If you have a lower strength, your physician may instruct you to use it 1 to 3 times daily. Carefully follow your doctor’s instructions.

The dosage will be determined based on your medical condition, response to treatment, and the prescribed strength.

During the course of treatment with this medication, ensure that you consume an ample amount of fluids unless otherwise advised by your doctor. Adequate hydration will help prevent the formation of kidney stones.

For optimal efficacy, have a bowel movement before utilizing this medication.

Before and after using the medication, wash your hands thoroughly. Unwrap the suppository just before use and handle it minimally to prevent melting caused by the heat from your fingers. Lie down on your left side with your right knee bent. Gently insert the suppository, pointed end first, into the rectum using your finger. If desired, a small amount of lubricating gel can be applied to the tip of the suppository. Maintain a lying position for a few minutes. To allow the medication to take effect, it is advisable to refrain from having a bowel movement for 1 to 3 hours, ensuring the suppository remains in place.

Be aware that this medication may cause staining on surfaces it comes into contact with, such as clothing, floors, and countertops.

To derive the maximum benefit from this medication, use it regularly at the same time(s) each day to aid in remembering.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • dizziness
  • rectal pain
  • acne
  • fever
  • inflammation of the large intestine (colitis)
  • rash

Inform your healthcare provider immediately if you experience any serious side effects:

  • cramps
  • fever
  • stomach (abdominal) pain
  • headache
  • bloody diarrhea
  • rash
  • chest pain
  • shortness of breath
  • decrease in the amount of urine
  • fatigue
  • eye inflammation


Prior to initiating the use of mesalamine, inform your healthcare provider or pharmacist about any known allergies to mesalamine, other aminosalicylates, salicylates, sulfasalazine, or any other substances. Inactive ingredients present in this product may also trigger allergic reactions or other complications.

Before using this medication, disclose your complete medical history to your doctor or pharmacist, particularly if you have a history of kidney problems, liver disease, pancreas problems (pancreatitis), or inflammation of the pericardium (the sac surrounding the heart).

This medication may increase your sensitivity to sunlight, particularly if you have existing skin conditions such as atopic dermatitis or eczema. Limit your sun exposure, avoid tanning beds and sunlamps, and ensure you use sunscreen and wear protective clothing when outdoors. Promptly inform your doctor if you experience sunburn or notice any skin blisters or redness.

This medication shares similarities with aspirin. Individuals under the age of 18, including children and teenagers, should avoid taking aspirin or related medications (such as salicylates) if they have chickenpox, flu, an undiagnosed illness, or have recently received a live virus vaccine (such as varicella vaccine). Consult a doctor beforehand due to the potential risk of Reye’s syndrome, a rare but serious condition.

During pregnancy, the use of this medication should only be considered if clearly necessary. Discuss the potential risks and benefits with your doctor.

This medication is excreted in breast milk and may have adverse effects on a nursing infant. Discuss the potential risks and benefits with your doctor before initiating breastfeeding.

Form and Strength

Canasa is available in the following forms and strengths:

  • Canasa (form)


How fast does Canasa work?

Canasa will begin working to decrease inflammation right after you take your first dose of medication.

Does it hurt to insert Canasa in the rectum?

Canasa can sometimes cause pain or discomfort when you’re inserting the suppository into your rectum.



Additional information

Generic name:



Rectal Suppository


500mg, 1000mg

Quantities Available:

30, 90

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Canasa (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Canasa (Mesalamine).