Delzicol (Mesalamine) Customer Reviews


Rx Prescription Required    RxFormulation : DR Capsule

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Mesalamine is utilized for the treatment of ulcerative colitis, a debilitating condition characterized by inflammation and ulceration in the colon’s lining, including the large intestine and rectum. This medication also serves the purpose of sustaining the improvement of ulcerative colitis symptoms.

Mesalamine belongs to the category of pharmacological agents known as anti-inflammatory medications. Its mechanism of action involves the inhibition of specific substances responsible for inducing inflammation, thereby impeding their production within the body.

Uses and Dosage

Mesalamine is available in various formulations designed to ensure optimal delivery and effectiveness in the intended area of the intestine. These include delayed-release tablets, delayed-release capsules, and extended-release capsules for oral administration.

The delayed-release tablets are typically taken once daily with food by both adults and children. For the delayed-release tablets, adults are advised to take them three times a day on an empty stomach, either one hour before or two hours after meals. The extended-release capsules are usually taken once daily in the morning, with or without food, by adults. The extended-release capsules are typically taken four times a day by adults, with or without food. In the case of the extended-release capsules, adults are advised to take them 2 to 4 times a day, with or without food, while children are instructed to take them twice a day, preferably in the morning and afternoon.

To ensure safe and effective use, carefully follow the instructions provided on the prescription label. Mesalamine should be taken precisely as directed, without exceeding or reducing the prescribed dosage or frequency as determined by your doctor.

The delayed-release tablets, delayed-release capsules, and extended-release capsules should be swallowed whole, without splitting, chewing, or crushing them. Extra caution should be exercised to avoid damaging the protective coating of the delayed-release tablets.

If swallowing the extended-release capsules is challenging, open the capsules and sprinkle the entire contents onto a tablespoon of applesauce or yogurt. The resulting mixture should be swallowed promptly, without chewing.

In the case of the delayed-release capsules, if swallowing is difficult, carefully opening the capsules and swallowing the entire contents (without chewing) is acceptable, followed by drinking a glass of water to ensure complete ingestion of the medication.

Adequate fluid intake should be maintained while taking mesalamine.

Continue taking mesalamine until you have completed the prescribed course of treatment, even if you experience initial improvements in your condition. Discontinuing mesalamine without consulting your doctor is not recommended.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • muscle or joint pain, aching, tightness or stiffness
  • back pain
  • nausea
  • vomiting
  • heartburn
  • burping
  • constipation
  • gas
  • dry mouth
  • itching
  • dizziness
  • sweating
  • acne
  • hair loss
  • decreased appetite

Inform your healthcare provider immediately if you experience any serious side effects:

  • rash, hives, itching or peeling or blistering skin
  • mouth sores or blisters
  • fever or flu-like symptoms
  • swelling of the eyes, face, lips, tongue, mouth, or throat
  • swollen glands
  • difficulty breathing or swallowing
  • new or worsening cough
  • chest pain
  • shortness of breath
  • black or tarry stools
  • bloody vomit
  • vomiting material that looks like coffee grounds
  • swelling of any part of the body
  • side or back pain
  • difficult or painful urination, or pink or red colored urine, or blood in urine
  • extreme tiredness
  • yellowing of the skin or eyes
  • pain in the right upper part of the stomach
  • pale stools


Prior to initiating mesalamine treatment, inform your doctor or pharmacist about any known allergies to mesalamine, other aminosalicylates (such as balsalazide, olsalazine), salicylates (such as aspirin, salsalate), sulfasalazine, or any other substances. This product may contain inactive ingredients that can trigger allergic reactions or other complications.

Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of kidney disease, liver disease, or stomach blockage (such as pyloric stenosis).

This medication may increase your skin’s sensitivity to sunlight, particularly if you have pre-existing skin conditions such as atopic dermatitis or eczema. Limit your sun exposure, avoid tanning booths and sunlamps, and employ sunscreen and protective clothing when outdoors. Should you experience sunburn or develop skin blisters/redness, promptly notify your doctor.

This medication shares similarities with aspirin. Consequently, children and teenagers under 18 years of age should refrain from taking aspirin or aspirin-related medications if they have chickenpox, flu, an undiagnosed illness, or have recently received a vaccine. The use of aspirin in such cases heightens the risk of Reye’s syndrome, a rare yet serious illness.

During pregnancy, the use of this medication should only be considered if clearly necessary. Discuss the potential risks and benefits with your doctor.

This medication is excreted into breast milk and may have adverse effects on nursing infants. Consult your doctor before breastfeeding while undergoing mesalamine treatment.

Form and Strength

Delzicol is available in the following forms and strengths:

  • Delzicol delayed-release capsule:

    • 400mg


How long can you take Delzicol?

For adults, the recommended dosage of Delzicol is two 400 mg capsules to be taken three times daily, for a duration of 6 weeks.

How long does it take for Delzicol to work?

Most people start to improve within 1 to 3 weeks after they start taking mesalamine. If you don’t get relief from symptoms that quickly, be patient. It can take up to 6 weeks for the medicine to put you into full remission.



Additional information

Generic name:



DR Capsule



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Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Delzicol (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Delzicol (Mesalamine).