Apriso (Mesalamine) Customer Reviews


Rx Prescription Required    RxFormulation : ER Capsule

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Generic alternative for Apriso


Rx Prescription Required    RxFormulation : ER Capsule

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Mesalamine is indicated for the treatment of ulcerative colitis, a chronic inflammatory disorder characterized by inflammation and ulceration in the colon and rectal lining. It is additionally utilized for the maintenance of remission in patients with ulcerative colitis symptoms. Mesalamine belongs to a pharmacological class known as anti-inflammatory agents, and its mechanism of action involves inhibiting the synthesis of a specific substance responsible for inducing inflammation within the body.

Uses and Dosage

Mesalamine is available in different formulations, including delayed-release tablets, delayed-release capsules, and extended-release capsules, all of which are taken orally.

The delayed-release tablets are typically administered once daily with food by both adults and children. As for the delayed-release tablets, they are usually taken three times daily on an empty stomach (either one hour before or two hours after meals) by adults. The extended-release capsules are generally taken once daily in the morning, with or without food, by adults. For the extended-release capsules, adults typically take them four times daily, with or without food. The extended-release capsules are taken with or without food 2 to 4 times daily by adults and twice daily by children, preferably in the morning and afternoon.

Carefully follow the instructions on your prescription label, and if there are any aspects you do not comprehend, consult your doctor or pharmacist for clarification. Take mesalamine precisely as directed, neither exceeding nor reducing the prescribed dosage, and adhere to the recommended frequency.

Swallow the delayed-release tablets, delayed-release capsules, and extended-release capsules whole, without splitting, chewing, or crushing them. Exercise caution to avoid damaging the protective coating of the delayed-release tablets.

In the event that you find it challenging to swallow the extended-release capsules, you have the option to open the capsules and sprinkle the entire contents onto a tablespoon of applesauce or yogurt. Consume this mixture immediately after preparation, without chewing it.

If swallowing the delayed-release capsules becomes problematic, carefully open the capsules, swallow the entire contents of each capsule (without chewing), and then drink a glass of water to ensure that all the medication has been ingested.

While taking mesalamine, remain adequately hydrated by consuming ample fluids.

Continue the course of mesalamine until you have completed the prescribed regimen, even if you experience initial improvement. Do not discontinue mesalamine without consulting your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • muscle or joint pain, aching, tightness or stiffness
  • back pain
  • nausea
  • vomiting
  • heartburn
  • burping
  • constipation
  • gas
  • dry mouth
  • itching
  • dizziness
  • sweating
  • acne
  • hair loss
  • decreased appetite

Inform your healthcare provider immediately if you experience any serious side effects:

  • rash, hives, itching or peeling or blistering skin
  • mouth sores or blisters
  • fever or flu-like symptoms
  • swelling of the eyes, face, lips, tongue, mouth, or throat
  • swollen glands
  • difficulty breathing or swallowing
  • new or worsening cough
  • chest pain
  • shortness of breath
  • black or tarry stools
  • bloody vomit
  • vomiting material that looks like coffee grounds
  • swelling of any part of the body
  • side or back pain
  • difficult or painful urination, or pink or red colored urine, or blood in urine
  • extreme tiredness
  • yellowing of the skin or eyes
  • pain in the right upper part of the stomach
  • pale stools


Prior to initiating mesalamine therapy, inform your healthcare provider or pharmacist about any known allergies to mesalamine, other aminosalicylates (such as balsalazide, olsalazine), salicylates (such as aspirin, salsalate), sulfasalazine, or any other substances. This product may contain inactive ingredients that could trigger allergic reactions or other complications.

Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of kidney disease, liver disease, or stomach blockage (e.g., pyloric stenosis).

This medication can increase sensitivity to sunlight, especially in individuals with pre-existing skin conditions (such as atopic dermatitis, eczema). Limit sun exposure, avoid tanning booths and sunlamps, and use sunscreen and protective clothing when outdoors. Promptly notify your doctor if you experience sunburn or develop skin blisters or redness.

Please be aware that this medication may contain aspartame. If you have phenylketonuria (PKU) or any other condition that necessitates restricting or avoiding aspartame (or phenylalanine) in your diet, consult your doctor or pharmacist to ensure the safe use of this medication.

This medication shares similarities with aspirin. Children and teenagers below the age of 18 should refrain from using aspirin or aspirin-related medications (such as salicylates) if they have chickenpox, flu, an undiagnosed illness, or have recently received a vaccine. In such cases, taking aspirin heightens the risk of developing Reye’s syndrome, a rare yet severe condition.

During pregnancy, the use of this medication should only be considered if the benefits clearly outweigh the potential risks. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have adverse effects on nursing infants. Consult your doctor before breastfeeding while undergoing treatment.

Form and Strength

Apriso is available in the following forms and strengths:

  • Apriso extended-release capsule:

    • 0.375mg
  • mesalamine extended-release capsule:

    • 0.375mg


Does Apriso have steroids in it?

No, Apriso isn’t a steroid. It’s an aminosalicylate drug. It works to reduce inflammation in your large intestine.

Will I have weight gain with Apriso?

No, changes in weight aren’t a known side effect of Apriso.


  1. https://www.healthline.com/health/drugs/apriso#fa-qs
  2. https://medlineplus.gov/druginfo/meds/a688021.html
  3. https://www.webmd.com/drugs/2/drug-151692/apriso-oral/details
  4. https://www.mayoclinic.org/drugs-supplements/mesalamine-oral-route/description/drg-20064708
  5. https://www.drugs.com/apriso.html

Additional information

Generic name:



ER Capsule



Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Apriso (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Apriso (Mesalamine).