Asacol HD (Mesalamine) Customer Reviews

Asacol HD

Rx Prescription Required    RxFormulation : Delayed Release Tablet (Enteric Coated)

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Generic alternative for Asacol HD


Rx Prescription Required    RxFormulation : Delayed Release Tablet (Enteric Coated)

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Mesalamine is employed in the treatment of ulcerative colitis, a condition characterized by inflammation and sores in the lining of the colon (large intestine) and rectum. Additionally, it is used to sustain the improvement of symptoms associated with ulcerative colitis. Mesalamine belongs to a class of medications known as anti-inflammatory agents. Its mechanism of action involves inhibiting the body’s production of a specific substance that has the potential to induce inflammation.

Uses and Dosage

Take this medication orally, with or without food, as instructed by your doctor, usually three times a day. For some brands, it is recommended to take them on an empty stomach, either at least 1 hour before or 2 hours after a meal. Consult your doctor or pharmacist for specific instructions related to your particular brand.

Swallow the medication whole; do not crush, chew, or break it. Doing so could hinder the proper release of the drug into the colon.

Ensure you stay well-hydrated during the course of this medication unless otherwise directed by your doctor. Adequate fluid intake can help prevent the formation of kidney stones.

The dosage is determined by your medical condition and response to treatment. In children, the dosage may also be based on weight. Different brands may deliver varying amounts of medication. Do not switch brands without your doctor’s approval and specific instructions.

Consistently use this medication to maximize its benefits. To aid in remembering, take it at the same times each day.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • muscle or joint pain, aching, tightness or stiffness
  • back pain
  • nausea
  • vomiting
  • heartburn
  • burping
  • constipation
  • gas
  • dry mouth
  • itching
  • dizziness
  • sweating
  • acne
  • hair loss
  • decreased appetite

Inform your healthcare provider immediately if you experience any serious side effects:

  • swelling of the eyes, face, lips, tongue, mouth, or throat
  • swollen glands
  • difficulty breathing or swallowing
  • new or worsening cough
  • chest pain
  • shortness of breath
  • black or tarry stools
  • bloody vomit
  • vomiting material that looks like coffee grounds
  • swelling of any part of the body
  • side or back pain
  • difficult or painful urination, or pink or red colored urine, or blood in urine
  • extreme tiredness
  • yellowing of the skin or eyes
  • pain in the right upper part of the stomach
  • pale stools


  • Before taking mesalamine, inform your doctor or pharmacist if you have allergies to mesalamine, other aminosalicylates, salicylates (such as aspirin, salsalate), sulfasalazine, or if you have any other allergies. Inactive ingredients in the product may trigger allergic reactions or other complications.
  • Before using this medication, share your medical history with your doctor or pharmacist, especially if you have kidney disease, liver disease, or stomach blockage (such as pyloric stenosis).
  • This medication may increase your sensitivity to the sun, particularly if you have skin problems like atopic dermatitis or eczema. Limit your sun exposure, avoid tanning booths and sunlamps, and use sunscreen while wearing protective clothing outdoors. Inform your doctor promptly if you experience sunburn or skin blisters/redness.
  • As this medication is similar to aspirin, it is not recommended for children and teenagers under 18 years old, especially if they have chickenpox, flu, or any undiagnosed illness, or if they have recently received a vaccine. In such cases, taking aspirin increases the risk of Reye’s syndrome, a rare but serious illness.
  • During pregnancy, use this medication only if clearly needed, and discuss the risks and benefits with your doctor.
  • This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Form and Strength

Asacol HD is available in the following forms and strengths:

  • Asacol HD delayed-release tablet:
    • 800 mg
  • mesalamine delayed-release tablet:
    • 800 mg


Why was Asacol HD taken off the market?

Asacol and Asacol HD both contained an inactive ingredient called dibutyl phthalate (DBP). DBP has the potential to be toxic, especially in young children and pregnant women.

Can Asacol HD be taken long term?

You’ll typically take the drug for 6 weeks to reduce inflammation in your colon and help relieve UC symptoms. It’s not known if Asacol HD is safe or effective to take for more than 6 weeks.



Additional information

Generic name:



Delayed Release Tablet (Enteric Coated)



Quantities Available:

84, 90, 100, 150, 168, 200, 270, 300

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Asacol HD (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Asacol HD (Mesalamine).