What is Desyrel (Trazodone)?

Desyrel (Trazodone) is an antidepressant medication used to treat depression. It affects brain chemicals that may become unbalanced causing depression. Desyrel works by preventing this re-absorption of serotonin back into the nerve cells.

Before using Desyrel, tell your doctor if you are allergic to Desyrel or to any other drugs, you are pregnant or plan to become pregnant or are breast-feeding a baby during treatment. Tell your doctor about all prescription and over-the-counter medications, vitamins, minerals and herbal products that you currently use.

Tell your doctor if you are/have:

  • Bipolar disorder (manic depression)
  • Schizophrenia or other psychiatric illness
  • A history of drug abuse or suicidal thoughts
  • If you have recently had a heart attack

Precautions to be taken:

  • Desyrel works best if you take it after a meal or a snack.
  • You may have thoughts of suicide when you first start taking an antidepressant, if you are younger than 24 years old.
  • Your blood will need to be tested on a regular basis.
  • If you need to have any type of surgery, tell the surgeon ahead of time that you are using Desyrel.
  • Stop taking Desyrel if you have a penis erection that is painful or lasts 4 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery.
  • Desyrel can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
  • Do not drink alcohol while you are taking Desyrel. Alcohol can increase drowsiness and dizziness caused by Desyrel.

How is Desyrel taken?

Follow the instruction of your doctor or the medication bottle label/pamphlet as prescribed to you. Your doctor may change the dosage to give you the best result. Take Desyrel after a meal or snack. Do not take Desyrel in large amounts. Do not take medication longer than suggested by your doctor.

Side effects of Desyrel

Serious side effects:

  • Feeling light-headed, fainting
  • Fever, chills, body aches, flu symptoms
  • Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
  • Problems with urination

Less serious side effects:

  • Dizziness or drowsiness
  • Headache
  • Sleep problems (insomnia)
  • Dry mouth, stuffy nose
  • Nausea, vomiting, loss of appetite
  • Diarrhea or constipation
  • Muscle pain
  • Loss of coordination
  • Blurred vision

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