Sucralfate is indicated for the treatment and prevention of duodenal ulcers, which are located in the initial segment of the small intestine. In cases where the ulcers are caused by Helicobacter pylori bacteria, additional medication, such as antibiotics, may be required for effective treatment and prevention of recurrence.
Sucralfate belongs to the class of protectant medications, and its mechanism of action involves binding to the damaged tissue of the ulcer and forming a protective barrier against acid and enzymes, thereby promoting healing.
Uses and Dosage
Administer this medication orally, typically 2 to 4 times daily, on an empty stomach at least one hour prior to a meal, or as per the guidance of your healthcare provider. The prescribed dosage is determined by your medical condition and response to treatment.
Consistently utilize this medication to achieve optimal benefit. To facilitate recollection, administer it at the same time each day.
Even in the absence of ulcer pain, continue taking this medication as instructed by your doctor. Cease usage only upon consulting your healthcare provider, as it may take 4 to 8 weeks for your ulcer to heal completely.
Certain medications may not function optimally if taken simultaneously with sucralfate, necessitating a different dosing schedule than that of sucralfate.
Antacids can be taken with this medication, but they must be ingested at least 30 minutes before or after sucralfate.
Notify your doctor if your condition persists or worsens after taking sucralfate for four weeks.
Some side effects may occur that usually do not need medical attention:
Inform your healthcare provider immediately if you experience any serious side effects:
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, or lips
Prior to initiating sucralfate therapy, inform your doctor or pharmacist of any allergies you may have, including allergies to sucralfate or other substances present in the medication’s inactive ingredients, as they can result in allergic reactions or other complications.
Before commencing usage of this medication, inform your doctor or pharmacist of your medical history, particularly if you have kidney problems, difficulty swallowing, a history of aspiration, stomach/intestinal issues such as delayed gastric emptying, or if you are being fed through a tube or utilizing a breathing tube (tracheotomy).
As you age, your kidney function may decline. This medication contains aluminum, which is typically removed by your kidneys. Elderly individuals may be at increased risk of developing high levels of aluminum while taking this medication concomitantly with other products containing aluminum.
If you are pregnant, inform your doctor prior to initiating sucralfate therapy.
It is unclear whether this medication passes into breast milk. Consult your doctor before breastfeeding.
Form and Strength
Carafate is available in the following forms and strengths:
How long does it take for Carafate to work?
Carafate may take 1–2 weeks to start healing an inflamed stomach. People should continue the medication for 4–8 weeks, depending on their doctor’s advice.
How long can you stay on Carafate?
Sucralfate is indicated for short-term treatment (up to 8 weeks) of active duodenal ulcer.