Uceris (Budesonide)

Description

Indications

Budesonide is employed in the treatment of Crohn’s disease, a condition characterized by the body’s immune system attacking the digestive tract lining. This can result in symptoms such as pain, diarrhea, weight loss, and fever. Budesonide belongs to a class of medications called corticosteroids, which operate by reducing inflammation (swelling) in the digestive tract for individuals with Crohn’s disease or in the kidney for those with nephropathy.

Uses and Dosage

Take this medication orally, with or without food, following the guidance of your doctor, typically once daily in the morning. Swallow the tablets whole with a full glass of water (8 ounces/240 milliliters), unless otherwise instructed by your doctor. Do not crush or chew the tablets, as this can lead to the rapid release of the entire dose, increasing the risk of side effects.

The dosage and duration of treatment are determined based on your medical condition and response to therapy.

Refrain from consuming grapefruit or grapefruit juice while on this medication unless your doctor or pharmacist advises it as safe. Grapefruit can elevate the likelihood of side effects when combined with this medicine. Seek further information from your doctor or pharmacist regarding this matter.

If you are on a regular regimen of another oral corticosteroid (such as prednisone), do not discontinue it unless instructed by your doctor. Some conditions (e.g., asthma, allergies) may deteriorate if the medication is abruptly ceased. Sudden cessation of the drug might also result in withdrawal symptoms. To mitigate withdrawal symptoms, your doctor may gradually reduce the dosage of your previous medication once you commence taking budesonide. Promptly inform your doctor or pharmacist if you experience withdrawal symptoms. Refer also to the Precautions section.

Adhere to a consistent schedule with this medication to maximize its benefits. To facilitate adherence, take it at the same time each day. Do not raise your dose or use this medication more frequently or for an extended period compared to what is prescribed. Doing so will not hasten your recovery and will heighten the risk of side effects.

Do not cease taking this medication without consulting your doctor, as certain conditions may worsen if the drug is abruptly discontinued. Your dosage may need to be gradually reduced.

Side Effects

Some side effects may occur that usually do not need medical attention:

• headache
• dizziness
• runny nose, sneezing, coughing
• nausea
• indigestion
• abdominal pain
• dry, itchy skin
• gas
• vomiting
• fatigue
• back pain
• pain
• muscle cramps

Inform your healthcare provider immediately if you experience any serious side effects:

• itching
• skin rash
• fever
• swelling of face and neck
• difficulty breathing
• severe headache
• changes in vision
• acne
• bruising
• swelling of the legs or arms
• fatty pad or hump between your shoulders

Caution

Prior to initiating budesonide treatment, inform your doctor if you have any allergies to this medication or other substances. Budesonide products may contain inactive ingredients capable of triggering allergic reactions or other complications.

Discuss your medical history with your doctor or pharmacist before using this medication, particularly if you have a history of eye problems, high blood pressure, liver disorders, diabetes, gastrointestinal issues, bone loss (osteoporosis), past or ongoing infections, bleeding disorders, or mental/mood disorders.

Prolonged usage of corticosteroid medications can hinder your body’s ability to respond to physical stress. Prior to surgery, emergency treatment, or if you experience a severe illness or injury, notify your doctor or dentist if you are currently using this medication or have used it in the past 12 months. Alert your doctor immediately if you develop unusual fatigue or experience unexplained weight loss. If you are on long-term medication, carry a warning card or wear a medical ID bracelet to identify your use of this medication.

While taking this medicine, limit alcohol consumption to reduce the risk of stomach bleeding. For additional information, consult your doctor or pharmacist.

Budesonide can increase your susceptibility to infections or exacerbate existing infections. Avoid contact with individuals who have infections that can be easily transmitted (e.g., chickenpox, COVID-19, measles, flu). If you have been exposed to an infection or require further details, speak with your doctor.

Notify your healthcare provider that you are using budesonide before receiving any immunizations or vaccinations. Steer clear of individuals who have recently received live vaccines.

In older adults, this drug’s side effects may be more pronounced, particularly bone loss/pain, gastrointestinal bleeding, and alterations in mental/mood.

Prolonged use of this medication in children may potentially impede their growth. Consult your doctor or pharmacist for more comprehensive information. Schedule regular check-ups with the doctor to monitor your child’s height and growth.

During pregnancy, only use this medication when it is absolutely necessary, following a thorough discussion of the risks and benefits with your doctor. Infants born to mothers who have been on corticosteroids for an extended duration may develop hormone-related issues. If you observe symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn, promptly inform your doctor.

This medication passes into breast milk. Discuss breastfeeding with your doctor before proceeding.

Form and Strength

Uceris is available in the following forms and strengths:

• Uceris extended-release tablet:
  • 9mg

FAQ

How long does it take for Uceris to work?

Uceris oral tablets worked within 8 weeks to induce remission in clinical trials.

How long do I need to take Uceris?

Most people typically take Uceris for up to 8 weeks. Your healthcare provider will tell you how long to take the medication based on your symptoms and the severity of your condition.

Resources

1. https://www.medicalnewstoday.com/articles/drugs-uceris#how-it-works
2. https://www.goodrx.com/budesonide-er/what-is#faqs
3. https://www.mayoclinic.org/drugs-supplements/budesonide-oral-route/description/drg-20073233
4. https://www.webmd.com/drugs/2/drug-163364/uceris-oral/details
5. https://medlineplus.gov/druginfo/meds/a608007.html
6. https://www.drugs.com/uceris.html