Orap is an antipsychotic used to treat serious muscle and speech tics in patients with Tourette syndrome. It works by blocking the action of dopamine, a naturally occurring chemical in the brain and controls automatic or unconscious movements (tics).

Before taking Orap, inform your doctors about the following: If you are pregnant, planning to become pregnant, or breast feeding; if you are allergic to any of its ingredients

Important information about Orap

Do not use this medicine in the management of manifestations of chronic schizophrenia in which the main symptoms include agitation, excitement and anxiety. Use caution while driving or operating machinery as it may cause drowsiness or dizziness. Avoid eating grapefruit or drinking grapefruit juice or alcohol while taking Orap.

Contact your health care provider at once if any of the following occur: Involuntary movements of tongue, face, mouth or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes accompanied by involuntary movements of the arms and legs. Neuroleptic malignant syndrome (NMS) has been associated with this medicine. Symptoms include increased body heat; rigid muscles; altered mental abilities, including lack of response to your surroundings; irregular pulse and blood pressure; increased heart rate; sweating; irregular heart rhythm. Contact your doctor at once if any of these symptoms occur.

Before taking Orap first discuss with your doctor if you:

  • have liver disease;
  • have kidney disease;
  • have heart disease or other heart problems such as high blood pressure, history of a heart attack, or irregular heartbeats;
  • suffer from seizures or epilepsy;
  • have an enlarged prostate or difficulty urinating;
  • have breast cancer;
  • have glaucoma.

Contact your health care provider if any of the following Parkinson-like symptoms occur: Muscle restlessness; tremors; drooling; muscle stiffness/rigidity; shuffling walk; unusual eye movements. Involuntary and uncontrollable movements may develop in patients taking this medicine. Occurrence is highest among the elderly, especially women. The risk of developing these involuntary movements and the likelihood they will become permanent are increased with long-term use and with high doses. However it is possible to develop these symptoms after short-term treatment at low doses.

Orap side effects

Serious Side Effects: Muscle restlessness; tremors; drooling; muscle stiffness/rigidity; shuffling walk; unusual eye movements; involuntary movements of tongue, face, mouth or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements.

Common Side Effects: Dry mouth; constipation; muscle tightness; stooped posture; impaired movement; stiffness; drowsiness; restlessness; speech problems; vision problems; impotence; changes in behavior. Diarrhea; headache; thirst; increased appetite; handwriting change; nervousness; changes in taste; sensitivity to light; depression.

This information is advisory only. It does not contain all information about this medication. If you have any questions about Orap, ask your doctor, pharmacist, or health care provider.

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