Pentasa (Mesalamine) Customer Reviews


Rx Prescription Required    RxFormulation : Slow Release Tablet

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Mesalamine is employed for the treatment of ulcerative colitis, a condition characterized by inflammation and ulcers in the lining of the colon and rectum. Additionally, it serves to sustain the progress achieved in alleviating symptoms of ulcerative colitis. Categorized as anti-inflammatory agents, mesalamine operates by impeding the body’s production of a specific substance known to trigger inflammation.

Uses and Dosage

Follow your doctor’s guidance and take this medication orally, usually four times a day. If you’re consuming the capsule form, you have the option to take it with or without food. For the tablet form, it’s recommended to take it with meals.

Ingest the medication whole—avoid crushing, chewing, or breaking it. These actions could disrupt proper drug release into the colon. If you encounter difficulties swallowing the capsule, you can open it and sprinkle the contents onto applesauce or yogurt prior to consumption. Swallow the entire mixture, comprising the medication and food, immediately without chewing. Refrain from chewing the mixture or preparing it in advance.

Ensure you maintain adequate fluid intake during treatment with this medication, unless your doctor instructs otherwise. Adequate fluid consumption assists in preventing the formation of kidney stones.

The prescribed dosage hinges on your medical condition and your response to the treatment.

To derive maximum benefit from this medication, adhere to a regular usage schedule. To enhance recollection, take it at consistent times each day.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • muscle or joint pain, aching, tightness or stiffness
  • back pain
  • nausea
  • vomiting
  • heartburn
  • burping
  • constipation
  • gas
  • dry mouth
  • itching
  • dizziness
  • sweating
  • acne
  • hair loss
  • decreased appetite

Inform your healthcare provider immediately if you experience any serious side effects:

  • rash, hives, itching or peeling or blistering skin
  • mouth sores or blisters
  • fever or flu-like symptoms
  • swelling of the eyes, face, lips, tongue, mouth, or throat
  • swollen glands
  • difficulty breathing or swallowing
  • new or worsening cough
  • chest pain
  • shortness of breath
  • black or tarry stools
  • bloody vomit
  • vomiting material that looks like coffee grounds
  • swelling of any part of the body
  • side or back pain
  • difficult or painful urination, or pink or red colored urine, or blood in urine
  • extreme tiredness
  • yellowing of the skin or eyes
  • pain in the right upper part of the stomach
  • pale stools


Prior to initiating mesalamine, inform your doctor or pharmacist about any allergic reactions you may have, whether to mesalamine itself, other aminosalicylates, salicylates, sulfasalazine, or any other allergens. This product may contain inactive components capable of triggering allergic reactions or other complications.

Before utilizing this medication, disclose your medical history to your doctor or pharmacist, particularly if you have kidney disease, liver disease, or stomach blockage (like pyloric stenosis).

This medication might heighten your sensitivity to sunlight, especially if you have skin conditions like atopic dermatitis or eczema. Be cautious when exposed to sunlight. Refrain from using tanning booths and sunlamps, and ensure you use sunscreen and protective clothing when outdoors. Should you experience sunburn or skin blisters/redness, promptly inform your doctor.

This medication possesses similarities to aspirin. Children and adolescents below 18 years of age should refrain from taking aspirin or aspirin-related medications (such as salicylates) if they have chickenpox, the flu, an undiagnosed illness, or have recently received a vaccine. In these scenarios, the consumption of aspirin heightens the risk of a rare yet serious condition known as Reye’s syndrome.

During pregnancy, employ this medication exclusively if its necessity is apparent. Discuss potential risks and benefits with your doctor.

This medication passes into breast milk and may have unfavorable effects on a nursing infant. Consult your doctor prior to breastfeeding.

Form and Strength

Pentasa is available in the following forms and strengths:

  • Pentasa prolonged release tablet:

    • 500mg


Is Pentasa an immunosuppressant?

No, Pentasa is not an immunosuppressant. Instead, Pentasa belongs to a class of drugs called aminosalicylates.

How long does it take for Pentasa to work?

Pentasa starts working to reduce inflammation in your bowel right away. But it may take a few weeks before your symptoms improve.



Additional information

Generic name:



Slow Release Tablet



Quantities Available:

100, 200

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Pentasa (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Pentasa (Mesalamine).