February 22, 2012

Possible Genetic Birth Defects in Children of Older Men

Filed under: birth defect — robertprice @ 8:58 pm

genetic disease in childrenIf you’re a middle aged male concerned about maximizing your future child’s health, you may want to think twice about dosing off to sleep versus staying awake to your own biological imperative.

New Dutch research is showing that men who snooze might be losing some of their child’s genetic material to possible genetic birth defects. These findings are based on 118 children whose genome, or genetic code, that were analyzed at Radboud University Nijmegen Medical Centre in the Netherlands.

Lead researcher, Jayne Hehir-Kwa explained, “We were looking at a specific form of genetic mutation which we find in some children with an intellectual disability.” In other words, diseases that are genetic.

In the cases in question, both of the parents of the child are healthy (genetically), but the child is born with missing, repeated, inverted or misplaced DNA sequences.

DNA is packed into 23 pairs of chromosomes. Half of the genetic material comes from the father, and half from the mother.

Researchers were concerned with genetic disease in children, trying to determine which parent bore responsibility for the defective DNA. “We found there was a strong bias towards the father’s DNA,” said Dr. Hehir-Kwa.

The results of the study were statistically significant: 90 out of the 118 children with the genetic birth defects were links to the fathers. The older the male, the higher the assumed risk for fathering a child born with as genetic birth defect.

Earlier research has also suggested that older men may be at higher risk for not only developing some sort of genetic disease in children, but also developing other diseases like schizophrenia. However, “this is the first study linking these genetic mutations for intellectual disability to the father’s age,” said Dr. Hehir-Kwa.

The findings were published in the Journal of Medical Genetics, and Hehir-Kwa suspects the problem arises from faulty sperm production in the older men. This causes the subsequent genetic birth defects.

The results of the study should not be taken to represent one of the major causes of genetic diseases in children. Intellectual disabilities occur at a rate of 1 per cent of births, and “the [genetic] variants we looked explain 10 percent of that 1 per cent,” Hehir-Kwa said.

Preborn children are extremely susceptible to a myriad of environmental factors which can have long term effects. In an other study a correlation between smoking while pregnant and an increased risk of becoming a criminal was explored.

With the above in mind: life is short, and full of dangers to your child. In the case of having healthy children, it seems to make sense to ‘live for the moment’ as opposed to the future. A man thereby inflates his chances to a rigid assurance that he is not endangering their child’s genetic opportunities. In other words, men, if she’s not in the mood, show her this article.

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November 5, 2009

Recent Study Shows Link Between Two Types of Antibiotic and Birth Defects


For many women, having children is the most important thing they will ever do. We are programmed genetically to reproduce in order to allow our species to survive. We are animals, and like many animals, we protect our young. This need to protect our children is also why it is scary that two common antibiotics have recently been linked to causing birth defects.

A recent study showed that two common antibiotics may cause birth defects. The two drugs in the study were nitrofurantoins (sold under the brand names Macrobid and Furadantin) and sulfa drugs (sold under the names Bactrim and Thiosulfil Forte). However, this was only the first study to show these results and further testing will be needed in order to confirm any real findings.

This does not mean that ALL antibiotics will cause birth defects. The only thing these findings mean is that you have to talk with your doctor about taking certain medications. You need to understand what some of these different medicines do. You must weigh the potential risks of the drug against the benefits. Take some time to really find out all the courses of action.

CanDrugstore.com, a Canadian Internet-based pharmacy intermediary (license #BC X23), offers low cost, long-term prescription drugs. A professionally registered pharmacist fills all Canadian prescriptions. A certified member of the Canadian International Pharmacy Association, CanDrugstore.com is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. For more information on how to order your drugs from Canada safely and securely call 1-866-444-6376 or visit http://www.candrugstore.com/– a trusted and reliable Canadian online pharmacy since 2002.Read more: “CanDrugStore” – http://www.candrugstore.com/blog/#ixzz0EaSkHrOA&A;

CanDrugstore.com, a Canadian Internet-based pharmacy intermediary (license #BC X23), offers low cost, long-term prescription drugs. A professionally registered pharmacist fills all Canadian prescriptions. A certified member of the Canadian International Pharmacy Association, CanDrugstore.com is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. For more information on how to order your drugs from Canada safely and securely call 1-866-444-6376 or visit http://www.candrugstore.com/- a trusted and reliable Canadian online pharmacy since 2002.